Allele/Variant

Impdh1tm1Bmi

Species
Mus musculus
Symbol
Impdh1tm1Bmi
Category
allele
Allele of gene
Impdh1
Transgenic Constructs
None
Synonyms
  • IMPDH type I-
  • Impdh1-
Description
A PGK-neomycin resistance gene was inserted in exon 9 together with a deletion of sequence at the end of the exon coding for amino acids 323-331. This eliminates the 2 amino acids lining the IMP binding pocket. No detectable mRNA transcripts are formed and Western blot analysis indicates that there is no gene product in thymus, lungs, or lymphocytes.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations