Allele/Variant

Thratm1Brnt

Species
Mus musculus
Symbol
Thratm1Brnt
Category
allele
Allele of gene
Thra
Transgenic Constructs
None
Synonyms
  • P398H
  • TRalpha P398H
Description
A cytosine to adnenosine transversion point mutation was engineered in exon 9, using a "hit and run" strategey, affecting a proline to histidine missense mutation at codon 398 (P398H). The mutation is dominant-negative.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations