Pnlip^tm1Dyh

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Species

Mus musculus

Symbol

Pnlip^tm1Dyh

Category

allele

Allele of gene

Pnlip

Transgenic Constructs

None

Synonyms

• PTL^-

Description

Exon 4 was disrupted by a neomycin selection cassette inserted by homologous recombination. The targeted exon has been reported to be essential for enzymatic activity. Protein was undetected in homozygous mutant mice by Western blot analysis of pancreatic extracts. Triglyceride hydrolysis was reduced by approximately 90% in homozygous mutanat mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations