Allele/Variant

Grxcr1pi-tde

Species
Mus musculus
Symbol
Grxcr1pi-tde
Category
allele
Allele of gene
Grxcr1
Transgenic Constructs
None
Synonyms
  • PLAP26
Description
Multiple copies of a transgenic construct, consisting of the Roux Sarcoma Virus promoter adjoined to the entire coding region of the human placental alkaline phosphatase gene, inserted in tandem array in the middle of chromosome 5. Phenotypic characteristics segregated with transgene and were not observed in a different line with similar levels of expression, indicating the phenotype was largely due to the site of insertion. A non-complementation test demonstrated that the insertional mutation is allelic to pirouette. Further molecular analysis showed that the insertion is located in intron 1, 32 kb upstream of exon 2.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations