Allele/Variant

Tg(Fabp1-Ccnd1)4Rdb

Species
Mus musculus
Symbol
Tg(Fabp1-Ccnd1)4Rdb
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
This transgenic construct contains the mouse cyclin D1 gene driven by the rat fatty acid binding protein promoter. Transgenic mice overexpress cyclin D1 in the liver and epithelial cells of the small intestine and colon. A lower level of expression occurs in the kidneys. This line carries 20-fold more transgene copies than the F2 line, which itself carries multiple transgene copies.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations