Ercc4^tm1Fwa

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Species

Mus musculus

Symbol

Ercc4^tm1Fwa

Category

allele

Allele of gene

Ercc4

Transgenic Constructs

None

Synonyms

• XPF^m

Description

The endogenous exon 8 was replaced with a mutant version containing a nonsense mutation at codon 445. A single loxP site remained in intron 7 after the excision of a floxed neo cassette. Though the mutation was expected to generate a truncated transcript, message was undetected by RT-PCR analysis of homozygous mutant MEFs.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations