Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Lck*F505)3073Rmp
MGI:3032775Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Lck*F505)3073Rmp

Species
Mus musculus
Symbol
Tg(Lck*F505)3073Rmp
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • pLGF-C
  • pLGFC
Description
The transgene contains 1kb of genomic sequence 5' of the start codon and the entire coding sequence of the murine gene through exon 11. Exon 12 is derived from mouse cDNA sequence modified so that phenylalanine is coded for at position 505 rather than tyrosine. These fragments are linked to a 3' untranslated region segment from hGH containing a single polyadenylation site. The resulting transgene is under the control of the proximal promoter element of the mouse gene and results in the production of 6 pg of mRNA per ug of total RNA.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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