Dnm1^Ftfl

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Species

Mus musculus

Symbol

Dnm1^Ftfl

Category

allele

Allele of gene

Dnm1

Transgenic Constructs

None

Synonyms

• Dyn1^ftfl

Description

A single change of a G-to-A in the first of two alternatively spliced regions results in an alanine to threonine substitution at amino acid 408 (p.A408T). This mutation only affects the Dnm1ax isoform sequences; the a exon is spliced out in the Dnm1bx forms, resulting all three Dnm1ax transcripts being altered.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations