Allele/Variant

Qkitm1Imeg

Species
Mus musculus
Symbol
Qkitm1Imeg
Category
allele
Allele of gene
Qki
Transgenic Constructs
None
Synonyms
  • qkI-
Description
Part of intron 1 and the first part of the coding sequence in exon 2, which includes the initiation sequence and the codons for the first 44 amino acids, were replaced with an IRES and a betageo fusion gene. This removes the highly conserved QUA1 domain in the encoded protein. Absence of transcription of the endogenous gene was demonstrated by RT-PCR. Beta-galactosidase is expressed from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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