Allele/Variant

Myogtm1Sjb

Species
Mus musculus
Symbol
Myogtm1Sjb
Category
allele
Allele of gene
Myog
Transgenic Constructs
None
Synonyms
  • mygT87N
Description
To disrupt phosphorylation of the encoded protein at threonine 87, a threonine-to-asparagine substitution mutation was engineered in the basic DNA-binding region at codon 87 (T87N) of exon 1. A single frt site remained in intron after the excision of an frt-flanked neo cassette from the germline. Expression of the mutant transcript was verified by Northern blot analysis of homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations