Allele/Variant

Pappatm1Cac

Species
Mus musculus
Symbol
Pappatm1Cac
Category
allele
Allele of gene
Pappa
Transgenic Constructs
None
Synonyms
  • PAPP-A KO
  • Pappa-
Description
A neo cassette replaced 1.6 kb of the gene including most of exon 4. RT-PCR confirmed lack of expression and IGFBP4 proteolysis confirmed lack of Pappa activity in homozygous mutants.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations