Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Cryaa-cre)10Mlr
MGI:3038243Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Cryaa-cre)10Mlr

Species
Mus musculus
Symbol
Tg(Cryaa-cre)10Mlr
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CPV14/Cre
  • cry-cre
Description
The expression of sequence encoding cre recombinase was driven by a modified alpha A crystallin promoter. The promoter consists of -282/+43 of the mouse Cryaa gene with an inserted copy of Pax6 consensus binding site in a 5' to 3' orientation at position -86 of the promoter. Seven lines were created with this line having expression of the transgene in both the lens epithelium and lens fiber cells but not in other parts of the eye.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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