Allele/Variant

Tg(CMV-Rpgr)1Tili

Species
Mus musculus
Symbol
Tg(CMV-Rpgr)1Tili
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
A mouse Rpgr ORF15 variant cDNA was inserted between the cytomegalovirus (CMV) enhancer promoter and the polyadenylation sequence of bovine growth hormone. The cDNA used in this construct is shortened by 654 base pairs in the purine-rich region of the ORF15 exon when compared to the published sequence of the 129/Sv mouse strain. This construct was used to generate transgenic mice by pronuclear injection. Transgene protein accumulates to a much lower level than the endogenous protein and migrated at a size smaller than the native protein.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations