Version: 8.0.0
Date: Tue Jan 28 2025
Trp53tm2.1Tyj
MGI:3039264
Allele of Trp53
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Trp53tm2.1Tyj

Species
Mus musculus
Symbol
Trp53tm2.1Tyj
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53 R172H
  • p53R172H
Description
The loxP site flanked STOP cassette was removed from Trp53tm2Tyj via Cre-mediated recombination, allowing the expression of a p.R172H missense mutation (G>A) in exon 5. Quantitative RT-PCR confirmed that the point mutation allele is expressed at a level comparable to wild-type.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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