Dnaja3^tm1.2Jdl

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Species

Mus musculus

Symbol

Dnaja3^tm1.2Jdl

Category

allele

Allele of gene

Dnaja3

Transgenic Constructs

None

Synonyms

• Td1^-

Description

Cre-mediated recombination removed the floxed exon 2 in Dnaja3^tm1Jdl, creating a frame-shift that putatively disrupted translation of the Dnaj domain, a glycine-and phenylalanine-rich region, a systein-rich part resembling a zinc finger, and a nonhomologous C-terminal domain. Western blot of mutant MEFs demonstrated that protein production was abolished.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations