Allele/Variant

Tpm3tm1Pgun

Species
Mus musculus
Symbol
Tpm3tm1Pgun
Category
allele
Allele of gene
Tpm3
Transgenic Constructs
None
Synonyms
None
Description
A single loxP site remained in place of the first coding exon (1b) and the donor splice junction following the excision of a floxed neo cassette by transient Cre-mediated recombination. This mutation was designed to eliminate all non-muscle type isoforms of the encoded protein. Western blot showed that protein levels in heterozygote brains were the same as that of wild-type.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations