Allele/Variant

Acetm5Keb

Species
Mus musculus
Symbol
Acetm5Keb
Category
allele
Allele of gene
Ace
Transgenic Constructs
None
Synonyms
  • ACE.7
Description
An allele carrying point mutations H395K and H399K in exon 8 was inserted via homologous recombination. Inactivation of the N-terminal catalytic site was confirmed using an N-terminal specific substrate. Expression of the mutant protein was shown to be equivalent to expression of the normal protein by western blot analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations