Version: 8.0.0
Date: Tue Jan 28 2025
Nrxn2tm1Sud
MGI:3042719
Allele of Nrxn2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Nrxn2tm1Sud

Species
Mus musculus
Symbol
Nrxn2tm1Sud
Category
allele
Allele of gene
Nrxn2
Transgenic Constructs
None
Synonyms
None
Description
A neo cassette replaced the first exon, which contains the complete 5' UTR, start codon, signal peptide and the first LNS domain. Immunoblotting of mutant brain confirmed lack of protein expression. This knock-out affects the alpha isoform specifically. The beta isoform, transcribed from a downstream promoter, is not affected..
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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