Allele/Variant

Ckbtm1Bew

Species
Mus musculus
Symbol
Ckbtm1Bew
Category
allele
Allele of gene
Ckb
Transgenic Constructs
None
Synonyms
  • B-CK-
Description
Exon 2 including the translation start site was deleted and replaced with a neo-cassette via homologous recombination. Absence of RNA expression and enzyme activity were confirmed by northern blot analysis and activity assays.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Phenotype
Annotation details
Source
References
abnormal hippocampal mossy fiber morphology
MGI
abnormal spatial learning
MGI
decreased susceptibility to pharmacologically induced seizures
MGI
increased exploration in new environment
MGI
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Disease Associations