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Date: Fri Dec 13 2024
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Ckb
tm1Bew
MGI:3042843
Allele of
Ckb
Mus musculus
Summary
Transgenic Constructs
Genomic Variant Information
Variant Molecular Consequences
Phenotypes
Disease Associations
Allele/Variant
Ckb
tm1Bew
Species
Mus musculus
Symbol
Ckb
tm1Bew
Category
allele
Allele of gene
Ckb
Transgenic Constructs
None
Synonyms
B-CK-
Description
Exon 2 including the translation start site was deleted and replaced with a neo-cassette via homologous recombination. Absence of RNA expression and enzyme activity were confirmed by northern blot analysis and activity assays.
Additional Information
Literature
Transgenic Constructs
No data available
Genomic Variant Information
No data available
Variant Molecular Consequences
Phenotypes
Phenotype
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Annotation details
Source
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References
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abnormal hippocampal mossy fiber morphology
View
Name
Type
Experimental condition
Modifier
References
Ckb
tm1Bew
/Ckb
tm1Bew
[background:] involves: 129P/Ola * C57BL/6
genotype
PMID:12059977
MGI
PMID:12059977
abnormal spatial learning
View
Name
Type
Experimental condition
Modifier
References
Ckb
tm1Bew
/Ckb
tm1Bew
[background:] involves: 129P/Ola * C57BL/6
genotype
PMID:12059977
MGI
PMID:12059977
decreased susceptibility to pharmacologically induced seizures
View
Name
Type
Experimental condition
Modifier
References
Ckb
tm1Bew
/Ckb
tm1Bew
[background:] involves: 129P/Ola * C57BL/6
genotype
PMID:12059977
MGI
PMID:12059977
increased exploration in new environment
View
Name
Type
Experimental condition
Modifier
References
Ckb
tm1Bew
/Ckb
tm1Bew
[background:] involves: 129P/Ola * C57BL/6
genotype
PMID:12059977
MGI
PMID:12059977
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