Neurl2^tm1Adz

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Species

Mus musculus

Symbol

Neurl2^tm1Adz

Category

allele

Allele of gene

Neurl2

Transgenic Constructs

None

Synonyms

• Ozz-

Description

A lacZ-pGK-Neo cassette was inserted into exon 1 via homologous recombination. Heart and skeletal muscle were shown to lack mRNA and protein expression in homozygotes. Ppgb mRNA and activity were also reduced in homozygotes but only to the level seen in Ppgb^tm1Adz heterozygotes which do not show any obvious abnormalities.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations