Allele/Variant

Igf2bp1Gt(OST33739)Lex

Species
Mus musculus
Symbol
Igf2bp1Gt(OST33739)Lex
Category
allele
Allele of gene
Igf2bp1
Transgenic Constructs
None
Synonyms
  • Igf2bp1Gt(Betageo)1Fcn
  • Imp1-
Description
A retroviral gene trap vector, containing a 5' LTR followed by a splice acceptor, beta-geo, PGK-puro, stop codons, a splice donor, and a 3' LTR, was inserted into intron 2. Insertion of the gene trap vector led to deletion of the second RNA recognition motif and the four K-homology modules, known to be essential for RNA binding, cytoplasmic granule formation, and subcytoplasmic localization. Normal transcript was undetected by RT-PCR analysis of homozygous mutant embryos.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations