Allele/Variant

Tg(Nefh-cre)12Kul

Species
Mus musculus
Symbol
Tg(Nefh-cre)12Kul
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Tg mNF-H-cre 12
Description
An 8.5 kb promoter fragment of mouse Nefh, containing the 5' UTR and 40 bp of non-coding sequence of exon 1 ending before the start codon, was adjoined to sequence encoding cre recombinase with an SV40 nuclear localization signal. An SV40 polyadenylation signal was also included in the construct. Expression of cre recombinase is driven in neurons of the brain and spinal cord during late development (around E18.5). Line 12 is best described and is representative of the other lines.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations