Allele/Variant

Fgf15tm1Sms

Species
Mus musculus
Symbol
Fgf15tm1Sms
Category
allele
Allele of gene
Fgf15
Transgenic Constructs
None
Synonyms
None
Description
The coding region of exon 3, which is the last coding exon, was replaced with a neomycin selection cassette inserted by homologous recombination. RT-PCR analysis of homozygous mutant embryos indicated an absence of normal transcript, but identified a mutant transcript containing exons 1 and 2. The mutant transcript lacks exon 3 sequence and therefore does not encode the putative HSPG and FGFR binding sites.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations