Version: 8.0.0
Date: Tue Jan 28 2025
Chuktm2Mka
MGI:3045616
Allele of Chuk
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Chuktm2Mka

Species
Mus musculus
Symbol
Chuktm2Mka
Category
allele
Allele of gene
Chuk
Transgenic Constructs
None
Synonyms
  • IkkaAA
  • IKKalphaAA
Description
Serines 176 and 180, located in exon 6, were replaced with alanines following homologous recombination. A floxed neo was excised from between exons 7 and 8 via transient Cre-mediated recombination. RT-PCR of liver tissue demonstrated expression of the mutant allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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