Allele/Variant

Tg(Igk-V21-Bax)1967Bvn

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

3'KE-Bcl-XL
KE/Bcl-XL

Description

This transgene consists of 3' enhancer and promoter sequence from the mouse Igk-V21, a flag epitope fused to mouse Bax cDNA, and the 3'UTR from the human growth hormone gene. The highest levels of expression of this transgene are found in the marrow, spleen and lymph nodes. Expression is also restricted to immature/transitional B cells. Three founder lines were generated 1962, 1967 and 2021.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Bax (Mmu)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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