Allele/Variant

Pargtm1Zqw

Species
Mus musculus
Symbol
Pargtm1Zqw
Category
allele
Allele of gene
Parg
Transgenic Constructs
None
Synonyms
  • Parg(110)
  • Parg(110)-
Description
Exons 2 and 3 were excised following transient Cre expression, leaving a single loxP site in intron 1. Western blot showed only a 60 kDa protein was present in mutants and wild-type, while wild-type also had a 110 kDa protein. RT-PCR confirmed that exons 2 and 3 had been deleted. RACE-PCR indicated presence of 2 variant transcripts in mutants: one transcript including exon 1 and exons 4 to 18 and the other only exons 4-18.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations