Allele/Variant

Tg(Apoa2)1Lus

Species
Mus musculus
Symbol
Tg(Apoa2)1Lus
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The transgene contains mouse apolipoprotein A-II sequence from Swiss 3T3 cells with 4.5 kb of upstream sequence and 8.5 kb of downstream sequence. About 10 copies of the transgene integrated into the genome. The apoA-II expressed from the Swiss 3T3 cell genomic clone carries a more basic apoA-II allele (found among many inbred strains of mice) than the C57BL/6J apoA-II allele. Expression of the transgene in the liver was 4-fold higher than endogenous gene expression.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations