Allele/Variant

Tnfrsf1atm1.1Gkl

Species
Mus musculus
Symbol
Tnfrsf1atm1.1Gkl
Category
allele
Allele of gene
Tnfrsf1a
Transgenic Constructs
None
Synonyms
  • P55deltaNS
Description
A targeting vector was designed to delete 15 nucleotides in exon 6 encoding amino acids 202-206. Southern blot and PCR confirmed recombination. Flow cytometry of peritoneal cells indicated that the mutation abolished receptor shedding. Cre-mediated recombination removed the floxed selection cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations