Allele/Variant

Cdk6tm1Bbd

Species
Mus musculus
Symbol
Cdk6tm1Bbd
Category
allele
Allele of gene
Cdk6
Transgenic Constructs
None
Synonyms
  • Cdk6-
Description
A PGK-neo cassette replaced the first coding exon, which contains the ATG as well as the PLSTIRE domain essential for cyclin binding. PCR confirmed recombination in mutant mice. Immunohistochemical analysis of lymphocytes indicated lack of protein expression in mutants.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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