Allele/Variant

Cd22tm2Tft

Species
Mus musculus
Symbol
Cd22tm2Tft
Category
allele
Allele of gene
Cd22
Transgenic Constructs
None
Synonyms
  • CD22AA
Description
R130 and R137 codons were targeted to generate codons encoding alanine residues. A floxed neomycin resistance gene was inserted between exons 4 and 5. Crossing with mice expressing Cre in the germ line excised the floxed neo. Immunoblot and flow cytometry confirmed protein was expressed in spleen cell lysates from mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations