Allele/Variant

Prkag3tm1Sson

Species
Mus musculus
Symbol
Prkag3tm1Sson
Category
allele
Allele of gene
Prkag3
Transgenic Constructs
None
Synonyms
  • AMPKgamma3 KO
  • gamma3 AMPK KO
Description
The insertion of a neomycin resistance gene resulted in the transcription of exons 1-4 joined to exons 11-13, with a frame shift after residue 211 and a premature stop codon at residue 235, skipping most of the 489 amino acids encoded by the wild-type transcript. Western blot showed the complete absence of wild-type protein in skeletal muscle.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations