Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Myl1-Prkag3*R225Q)1Sson
MGI:3055157Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Myl1-Prkag3*R225Q)1Sson

Species
Mus musculus
Symbol
Tg(Myl1-Prkag3*R225Q)1Sson
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • R225Q
  • Tg-Prkag3225Q
Description
A Myl1 promoter and enhancer drive expression of a full length mouse Prkag3 cDNA with a single missense mutation (R225Q). Expression of the mutated protein was seen in the skeletal muscle. Levels of the endogenous PRKAG3 protein were reduced resulting in no significant change in overall PRKAG3 protein expression.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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