Allele/Variant

Tg(PRG3)9Wlad

Species

Mus musculus

Symbol

Tg(PRG3)9Wlad

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

PRG3
TGM-PRG-3

Description

This line carries ten copies of the human poliovirus receptor transgene (PVR). The human polio virus receptor is a member of the Igg superfamily. Northern and Western blot analyses detected expression of the transgene at levels three times higher in mice carrying this transgene, compared to levels in transgenic mice carrying a single copy of human PVR.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

PVR (Hsa)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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