Version: 8.0.0
Date: Tue Jan 28 2025
Cacna2d2tm1Svi
MGI:3055290
Allele of Cacna2d2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cacna2d2tm1Svi

Species
Mus musculus
Symbol
Cacna2d2tm1Svi
Category
allele
Allele of gene
Cacna2d2
Transgenic Constructs
None
Synonyms
  • Cacna2d2tm1Ncif
Description
A neomycin resistance cassette replaced exons 33-39 of the gene. The replacement eliminated the delta subunit and the 87 C-terminal amino acids of the alpha-2 subunit of the protein. Northern blots of brain detected the truncated 5' mRNA and did not detect the 3' region. RT-PCR derived from brain did not detect the targeted 3' portion of the transcript.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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