Allele/Variant

Mettm1Kln

Species
Mus musculus
Symbol
Mettm1Kln
Category
allele
Allele of gene
Met
Transgenic Constructs
None
Synonyms
  • Met2P
Description
A mutant human cDNA coding for the transmembrane and cytoplasmic domains of the receptor was inserted in-frame into mouse genomic sequences. The mutations resulted in alterations of two multifunctional tyrosinase motifs: Y1349VHVNATY1356VNV to Y1349MDMSATY1356MDMS. A floxed neo included in the construct was excised by crossing with Cre deleter mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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