Allele/Variant

Lattm2.1Mal

Species
Mus musculus
Symbol
Lattm2.1Mal
Category
allele
Allele of gene
Lat
Transgenic Constructs
None
Synonyms
  • LatY7/8/9F
  • Lat3YF
Description
Tyrosine residues at positions 175, 195 and 235 (p.Y175F, p.Y195F, p.Y235F), in exons 9-11, respectively, were mutated to phenylalanine residues. Western blot shows that the amount of protein in mutant thymocytes is similar to that of wild-type. A floxed neo was inserted between exons 9 and 10 and subsequently removed by crossing with deleter mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations