Allele/Variant

Phox2atm1(Phox2b)Mist

Species
Mus musculus
Symbol
Phox2atm1(Phox2b)Mist
Category
allele
Allele of gene
Phox2a
Transgenic Constructs
None
Synonyms
  • Phox2aKI2b
Description
The Phox2b coding sequence was inserted upstream of exon 1 along with a floxed neo cassette which was later removed by cre-mediated recombination following a cross to Tg(ACTB-cre)1Nagy mice. The insertion creates a fusion protein. Southern blot analysis and PCR genotyping were used to confirm the insertion. Immunohistochemistry was used to confirm the alteration in expression patterns.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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