Allele/Variant

Top2btm2Jcw

Species
Mus musculus
Symbol
Top2btm2Jcw
Category
allele
Allele of gene
Top2b
Transgenic Constructs
None
Synonyms
  • top2betaflox1
  • top2betaflox2
Description
A self excising neomycin resistance cassette together with an upstream loxP site was inserted in one intron (4?) and a second loxP site was inserted in the third downstream exon. The presence or absence of the neomycin cassette was assessed by PCR but did not affect selection of mice for breeding since the resistance cassette was contained between the two loxP sites.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations