Macroh2a1^tm1Peh

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Species

Mus musculus

Symbol

Macroh2a1^tm1Peh

Category

allele

Allele of gene

Macroh2a1

Transgenic Constructs

None

Synonyms

• macroH2A1^-

Description

An IRESBgeo cassette was inserted in 1st intron. This cassette was flanked by LoxP sites and a 3rd loxP site was inserted in the 2nd intron. Transient cre expression removed the floxed sequence, including exon 2, which encodes the first part of the H2A domain. Western blot analysis confirmed the absence of protein product.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations