Sgk3^tm1Dpea

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Species

Mus musculus

Symbol

Sgk3^tm1Dpea

Category

allele

Allele of gene

Sgk3

Transgenic Constructs

None

Synonyms

• Sgk3^-

Description

The gene was disrupted by the deletion of part of exons 9 and 10 containing the ATP-binding site necessary for catalytic activity, and introducing an in-frame stop codon into exon 10. Northern blot of kidney, lung and thymus of mutants showed a lack of mRNA, and Western blot of kidney and liver confirmed a null protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations