Version: 8.0.0
Date: Tue Jan 28 2025
Tg(CAG-WRN*K577M)5025Wcl
MGI:3525073Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(CAG-WRN*K577M)5025Wcl

Species
Mus musculus
Symbol
Tg(CAG-WRN*K577M)5025Wcl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • K577-WRN
  • Tg(ACTB-WRN*K577M)5025Wcl
Description
The transgene is composed of a full length cDNA encoding human WRN with a mutation that alters lysine 577 to methionine expressed under the control of a cytomegalovirus enhancer and a chicken beta-actin promoter, and was followed by a rabbit beta-globin polyadenylation site.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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