The mutation of Il10ra cDNA nucleotides (GenBank accession number NM_008348) includes A-to-G transitions at position 160 and 466, C-to-T transitions at position 346, 475, 727, 1099, 1124, 1368, 1381, and 1750, TG-to-CC transitions at position 492 and 493, T-to-C transitions at position 553 and 1585, a G-to-A transition at position 1146, a G-to-C transition at position 1364, a A-to-T transition at position 1464, and a A-to-C transition at position 1707 in the coding region, and G-to-A transitions at position 1936, 2293, 2890 and 3144, a A-to-C transition at position 2002, a T-to-G transition at position 2100, A-to-G transitions at position 2194, 2319, 2485 and 3167, A-to-T transitions at position 2264 and 2341, C-to-T transitions at position 2665 and 3355,a T-to-C transition at position 2796, and a insertion of G between position 3082 and 3083 in the 3' untranslated region.