Allele/Variant

Txnrd1tm1.1Marc

Species
Mus musculus
Symbol
Txnrd1tm1.1Marc
Category
allele
Allele of gene
Txnrd1
Transgenic Constructs
None
Synonyms
  • Txnrd1-
Description
Exon 15, which encodes 22 amino acids and the C-terminally located redox center consisting of Gly-Cys-Sec-Gly, and 1.7 kb of the 3' UTR containing the selenocysteine insertion element, essential for cotranslational Sec incorporation at the UGA codon, AU-rich mRNA instability elements and the endogenous transcription stop signal, were deleted from Txnrd1tm1Marc via cre-mediated recombination. RT-PCR confirmed the excision of exon 15 in embryonic mRNAs from E9.5
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

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    Disease Associations

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