Sh2d1a^tm1Lyin

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Species

Mus musculus

Symbol

Sh2d1a^tm1Lyin

Category

allele

Allele of gene

Sh2d1a

Transgenic Constructs

None

Synonyms

• sap^-
• Sh2d1a^-

Description

A neomycin resistance gene replaced a sequence consisting of 606 bp of intron 1 and 25 bp of exon 2. RT-PCR and sequencing showed that the resulting transcript skipped exon 2, and therefore contained a 64 bp frame-shift deletion. Western blot demonstrated the lack of protein in mutant thymocytes.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations