Allele/Variant

Smpd3tm1Wst

Species
Mus musculus
Symbol
Smpd3tm1Wst
Category
allele
Allele of gene
Smpd3
Transgenic Constructs
None
Synonyms
  • smpd3-
Description
Exon 1 was interrupted by the insertion of a PGK-neo cassette. Exon 1 encodes the two putative transmembrane domains and part of the catalytic site of the protein. Northern blot of brains from mutants demonstrated the lack of wild-type transcript. Western blot of brain protein extract from mutants confirms absence of protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations