Alms1^Gt(XH152)Byg

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Species

Mus musculus

Symbol

Alms1^Gt(XH152)Byg

Category

allele

Allele of gene

Alms1

Transgenic Constructs

None

Synonyms

• Alms1^-
• Alms1^{Gt(pGT1Lxf)1Pjn}

Description

A gene trap vector (pGT1Lxf) containing a splice acceptor, lacZ and neomycin resistance gene was inserted into intron 13. RT-PCR showed strong expression upstream of the inserted cassette, however, expression downstream of exon 13 was not detected in mutants. Slight traces of normally spliced exon 13-14 were detected in mutants, suggesting the disruption might have resulted in a hypomorphic allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations