Version: 8.0.0
Date: Tue Jan 28 2025
Cbfbtm1Lhc
MGI:3579250
Allele of Cbfb
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cbfbtm1Lhc

Species
Mus musculus
Symbol
Cbfbtm1Lhc
Category
allele
Allele of gene
Cbfb
Transgenic Constructs
None
Synonyms
  • Cbfb56M
Description
ES cells containing Cbfbtm1Ppl were targeted a second time to insert a floxed cassette encompassing exons 5 and 6, as well as the bovine growth hormone polyA signal and a PGK-hygro cassette into the Msc1 site in intron 4. This design allows the wild-type Cbfb transcript to be expressed. Cre expression would remove the cassette and restore expression of the knockin allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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