Allele/Variant

Tg(GFAP)10Mes

Species
Mus musculus
Symbol
Tg(GFAP)10Mes
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • GFAPTg
  • TgN(GFAP)Mes10
Description
This transgene consists of a 17.5 kb fragment of DNA extending about 6 kb upstream to 1.5 kb downstream of the human GFAP gene, including regulatory elements sufficient to direct astrocyte-specific expression. Five lines were established 2 of which had high levels of expression in at least some mice (73.1 uniformly high expression and 73.7 about 20% with high expression). Line 73.7 was given a strain designation TgN(GFAP)Mes10. This is the representative record for both high expressing lines.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations