Allele/Variant

Itgaltm1Hlz

Species
Mus musculus
Symbol
Itgaltm1Hlz
Category
allele
Allele of gene
Itgal
Transgenic Constructs
None
Synonyms
  • Lfa-1d
Description
A constitutive germline deletion of the amino acid motif GFFKR in the membrane proximal segment of the cytoplasmic domain, was accomplished by insertion of a neomycin resistance cassette and a HSV-thymidine kinase cassette. The neo was later removed by crossing to a cre expressing strain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations