Allele/Variant

F11rGt(KST235)Byg

Species
Mus musculus
Symbol
F11rGt(KST235)Byg
Category
allele
Allele of gene
F11r
Transgenic Constructs
None
Synonyms
  • F11rGt(pGT1pfs)1Upn
  • JAM-A-
Description
A gene trap vector (pGT1TMpfs) insertion resulted in the fusion of the first Ig domain to TMbetageo, an artificial protein created from the transmembrane domain of rat Cd4 joined to the catalytically active domains of betagalactosidase and neomycin genes followed by an IRES and placental alkaline phosphatase reporter cassette. The betagalactosidase and neomycin genes are flanked by Frt sites. The absence of protein product in the endothelium of the aorta was confirmed by immunohistochemistry.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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